Technical set-up
isoprime precisION IRMS
isoprime precisION forms the core of your system, a starting point from which to grow your research. Maximize the possible analyses with your system by choosing any combination of inlet systems, and automatically switch between them using the centrION Continuous Flow Interface System, which is incorporated into the instrument.
Novel Inlet Control Module
Perhaps your research topic demands something different? Then you can interface isoprime precisION with your bespoke experimental system with the revolutionary Novel Inlet Control Module (NICM), which offers substantial control of additional I/O with the elegant Method Workflow Designer. Adding multi-collector arrays with bespoke amplification resistor configurations will drive your experiment even further.
Planning proactively for possible future research requirements is simple when you have an instrument that performs to the very highest levels. isoprime precisION offers the highest gas ionization performance and mass resolution, all in the most compact footprint possible.
lyticOS® Software Suite
Our lyticOS® Software Suite works in concert with isoprime precisION and centrION to provide an unrivalled level of intelligent control. Designed completely from the ground up for an exceptional user experience, lyticOS® is the most sophisticated yet simple software ever created. Its clean user interface belies the level of sophistication within, giving users unrivalled capabilities to generate exceptional data with ease.
A powerful yet simple tool, lyticOS® delivers a world of opportunity for your laboratory. With complete control of the hardware and simple programming with the Method Workflow Designer, you can continue expanding your research horizons over time.
Inlet Systems
We offer a broad portfolio of peripheral inlet systems designed specifically for stable isotope analysis. The choice of inlet system depends on your experimental requirements, but whichever inlet you choose, you can be sure that your samples are handled exactly and faithfully with absolutely no isotope fractionation. Complete automation and switching makes isoprime precisION the most dynamic and flexible stable isotope mass spectrometer ever created.
Elemental analysis
Conversion of bulk organics and inorganics in solid and liquid sample matrices into pure gases, prior to isotope analysis.
Chromatography
Column separation of complex organic mixtures using GC and LC techniques and converted into sample gases in real time.
Headspace
Preparation, separation and analysis of air, breath, liquid and carbonate samples, prepared into septum-sealed vials.
Gas analysis
Concentration and separation of various gaseous sample types prior to isotope analysis.
Key features
- 100 V amplification for large dynamic-range samples with auto resistor switching
- Simultaneous measurement of up to 10 ion beams across a ± 25 % mass range for multi-collector experiments
- Improved gas ionization performance of 1,100 molecules/ion (CO2 in CF mode)
- Improved mass resolution of 110 m/Δm (at 10 % valley separation)
- lyticOS® Method Workflow Designer for developing bespoke control of your instrument
- Handle up to six monitoring gases and five inlets with centrION Continuous Flow Interface System
- Vacuum-grade stainless steel analyzer for the highest vacuum performance, with optional bakeout
- Automatic control of every aspect of the hardware with lyticOS® Software Suite
- Bespoke DAC dual-resistor configurations for non-standard isotopomer distributions
- Instant instrument status recognition with color LED warnings
Great flexibility: Complete integration of all inlet systems, including novel inlets
- The system can be combined with a variety of continuous flow peripheral inlet systems – as well as dual inlet technologies for the measurement of water and carbonate materials – ensuring the broadest possible range of applications.
- Its centrION continuous flow interface system enables it to switch seamlessly between inlet systems, offering fully automated handling and dilution of sample gases. This simplicity and flexibility make your workflows more efficient, whatever your application.
- Simultaneous measurement of up to 10 ion beams across a ±25 % mass range for novel multi-collector experiments.
High sensitivity: Combining exceptional analytical power & unrivalled flexibility
- isoprime precisION is one of the most powerful stable isotope ratio mass spectrometers ever created, with exceptional ionization efficiency in both continuous flow and dual inlet modes.
- Combined with our dedicated range of inlet systems, this offers unrivalled limits of detection for the smallest sample sizes across any application.
Small footprint: Almost 50 % smaller than other IRMS
- isoprime precisION is the most compact fully functional isotope ratio mass spectrometer (IRMS) on the market, with a unique electrostatic filter for the isobaric separation of ²H-H and ³He isotopes. This allows the system to be almost 50 % smaller than any other IRMS, making it ideal for space-limited laboratories.
- Its benchtop design and integrated centrION continuous flow interface ensure easy operation without compromising on flexibility or performance.
High data quality: Complete control of the IRMS workflow
- Data quality is dependent on many factors, including sample preparation, analytical methodology and data interpretation.
- lyticOS® Software Suite provides an intuitive interface for IRMS workflows. It allows you to quickly and easily set-up stable isotope analysis experiments, import and export data, and interpret results.
- lyticOS® offers complete control of the entire IRMS workflow to ensure the very best quality results at every step. The software offers automatic, multi-point, multi-isotope calibration using standard reference materials, and provides instant access to statistical analyses – such as averages and standard deviations – for sample replicates.
Custom experimental set-up options: Novel Inlet Control Modules increase flexibility
- The Novel Inlet Control Module (NICM) is an optional hardware device offering a revolutionary approach to interfacing custom experimental set-ups with isoprime precisION.
- The lyticOS® Software Suite can even control multiple NICM boxes simultaneously, allowing you to run experiments that require more devices than it is possible to operate with a single NICM box, so there are no limits to the amount of control available.
- lyticOS® provides all the development tools needed to create a full control solution for custom inlets, without the need for specialist knowledge or programming skills. The intuitive software allows you to bring together all the different inputs and outputs for your devices into customizable dashboards.
Simple & effective data analysis: Database management via ArDB
- ArDB is a combined database management tool and analytics platform that can be optionally used alongside isoprime precisION and lyticOS® Software Suite to construct, maintain and manage a centralized database of analytical results – regardless of the analytical technique.
- Designed to handle the large quantities of data generated by modern high throughput technologies, ArDB simplifies data processing workflows, making it easier to discover the story behind your results.
- Powerful data visualization capabilities make discovering trends and relationships within datasets straightforward, while integrated multi-variate analysis tools enable analytical results to be statistically reduced for easier interpretation.
